LIPOPRINT® HDL SUBFRACTIONS TEST
FOR RESEARCH USE ONLY. NOT FOR DIAGNOSTIC USE.
HDL encompasses a heterogenous class of lipoprotein subclasses that differ in composition and physiological function, and may vary in their anti-atherogenic potential and utility as markers for CVD risk.
The Lipoprint HDL test is a convenient, non-denaturing, linear polyacrylamide gel electrophoresis method that separates and quantifies up to 10 HDL subfractions in serum or plasma.
The HDL subfractions are classified into three major subclasses: large buoyant HDL lipoproteins (HDL-L), intermediate HDL lipoproteins (HDL-I) and small-dense HDL lipoproteins (HDL-S). The Large HDL subclass (HDL-L) shows an inverse relationship with CVD risk while the Small HDL subclass (HDL-S) exhibits a direct relationship with CVD risk. The Lipoprint HDL test is used in clinical trials and other research studies involving humans and other species such as mice, guinea pigs, chimpanzees and pigs.